寶醫師在美國生殖醫學會年會獲奬

 

2015 ASRM

 

(全球最大的美國生殖醫學會)

 

 

陳啟煌醫師獲得研究論文海報第二名。

 

IMG 2597IMG 2621IMG 2633IMG 2623

IMG 2624IMG 2625IMG 2626

 

http://www.baopie.net/index.php/

 

陳啟煌醫師部落格/國際會議/208-2013

 

年美國生殖醫學會年會1300件參展作品

 

得到首獎

 

 

 

陳啟煌醫師學術成果及計畫

研究計劃
A. 九十二年度國科會研究計劃 (NSC 92-2314-B-016-078):
「兔子卵巢的冷凍保存及移植」主持人
B. 九十三年度國科會研究計劃 (NSC 93-2314-B-016-037):
「精索靜脈曲張對精蟲品質及細胞凋零的影響」主持人
C. 九十六年度 國科會研究計劃 (NSC 96-2314-B-016-023):
「研究有效的性腺冷凍保存與移植的方法及冷凍傷害機轉的動物模式」主持人
D. 九十七年度國科會研究計畫 (NSC 97-2314-B-016-012-MY2):
「以基因轉殖鼠冷光表現活體追蹤生殖保存與延續的動物模式」主持人
E. 九十七年度國科會研究計畫
「增進自體脂肪移植存活的研究─基因轉殖鼠冷光活體動物實驗」共同主持人
F. 九十九年度國科會研究計畫 (NSC 99-2314-B-016-013-MY3):
「移植冷凍保存的精原幹細胞以重建精子形成小鼠生殖保存-基因轉殖模式」主持人
G. 一百零二年度國科會研究計畫 (NSC 102-2314-B-038-045):
「以組織工程在生保存未成熟雄性睪丸的生殖能力-基因轉殖鼠模式」主持人
H. 一百零三年度科技部轉譯醫學研究計畫 (MOST 103-2321-B-038-008) 2 年:
「以基因轉殖冷光小鼠模式研究組織支架於卵巢移植之應用」主持人
學術會議
A. Congress: 20th World Congress of The International Federation of Fertility Societies (IFFS)
Dates: 2010/09/12-16 Place: Munich, Germany Funding: NSC-97-2314-B-016-012-MY2
Subject: Tracking the effects of immunosuppression by in vivo bioluminescence imaging after allotransplantation of
ovarian grafts.
B. Congress: Fertilink and International Ovarian Conference (IOC)
Dates: 2010/10/16-17 Place: Kyoto, Japan Funding: NSC-97-2314-B-016-012-MY2
Subject: Protective effect of a gonadotropin-releasing hormone analogue on chemotherapeutic agent-induced ovarian
gonadotoxicity: A mouse model. (優秀論文獎)
C. Congress: Taiwanese Society for Reproductive Medicine Annual Meeting (TSRM)
Dates: 2011/08/27-28 Place: Taiwan, Tainan Funding: NSC-99-2314-B-016-013-MY3
Subject: Protective effect of sphingosine 1-phosphate (S1P) on chemotherapeutic agent-induced ovarian gonadotoxicity.
(優秀論文獎)
D. Congress: American Society for Reproductive Medicine 67th Annual Meeting (ASRM)
Dates: 2011/10/15-19 Place: Orlando, Florida Funding: NSC-99-2314-B-016-013-MY3
Subject: Bioluminescence imaging (BLI) as a tool to evaluate germ cell in vitro and transplantation in vivo as fertility
preservation of prepubertal male mice.
E. Congress: The international Ovarian Conference (IOC)
Dates: 2012/03/17 Place: Tokyo, Japan Funding: NSC-99-2314-B-016-013-MY3
Subject: Tracking the development potential and the onset inhibition of primordial follicle of the cryopreserved murine
ovary with bioluminescent imaging (BLI) in vivo. (優秀論文獎)
F. Congress: Controversies in Cryopreservation of Reproductive cells, Tissue and Organs (CRYO)
Dates: 2013/03/21-23 Place: Berlin, Germany Funding: NSC-99-2314-B-016-013-MY3
Subject: Antiapoptotic agent sphingosine-l-phosphate(SlP) protects against ischemic reperfusion injury of vitrified murine
ovarian grafts
G. Congress: American Society for Reproductive Medicine 68th Annual Meeting (ASRM)
Dates: 2013/10/12-17 Place: Boston, USA Funding: NSC-102-2314-B-038-045
Subject: In vivo immature testicular tissue engineering for male fertility preservation - a transgenic mouse model.
(海報類第一名)
H. Congress: European Society of Human Reproduction and Embryology (ESHRE)
Dates: 2014/06/29-07/02 Place: Munich, Germany Funding: NSC-102-2314-B-038-045
Subject: In vivo optical imaging of immature mouse testicular tissue engineering by three-dimensional scaffolds for
pre-pubertal male fertility preservation
學術著作
First and Correspondence
1. Chen CH, Chen SG, Wu GJ, Wang J, Yu CP, Liu JY. Autologous heterotopic transplantation of intact rabbit ovary after
cryopreservation at -196℃. Fertil Steril 2006 Oct; 86 (3):1059-66. Impact factor: 4.295 (5.1%)
2. Chen CH, Chen IC, Wang YC, Liu JY, Wu GJ, Tzeng CR. Boy born after gender preselection following successive
gestational androgen excess of maternal luteoma and female disorders of sex development Fertil Steril 2009 Jun;
91(6):2732.e5-7. Epub 2008 Dec 24 Impact factor: 4.295 (5.1%)
First author
3. Chen CH, Huang YH, Lai WF, Wang CW, Hsu MI, Tzeng CR. Bioluminescence imaging (BLI) as a tool to evaluate germ
cell in vitro and transplantation in vivo as fertility preservation of prepubertal male mice. Fertility Sterility 2012 May; 97
(1) : 192-8. Impact factor: 4.295 (5.1%)
4. Chen CH, Zhang X, Confino E, Milad M, Kazer RR. Relationships between peak serum estradiol levels and treatment
outcome in in vitro fertilization cycles following embryo transfer on day 3 or day 5. Fertil Steril 2003; 80:75-9. Impact
factor: 4.295 (5.1%)
5. Chen CH, Huang RL, Yu MS, Wong LJC, Chao TF, and Chu TY. Hereditary nonpolyposis colorectal cancer with
gynecologic malignancies: report two families in Taiwan. J Formos Med Assoc 2001; 100:269-73. Impact factor: 1.695
(38%)
6. Chen CH, Lee SS, Chen DC, Chien HH, Chen IC, Chu YN, Liu JY, Chen WH, Wu GJ. Apoptosis and kinematics of
ejaculated spermatozoa in patients with varicocele. J Androl. 2004 May-Jun; 25(3):348-53. Impact factor: 1.694 (57.1%)
7. Chen CH, Yeh YC, Wu GJ, Huang YH, Thomas Lai WF, Liu JY, Tzeng CR. Tracking the rejection and survival of mouse
ovarian iso- and allografts in vivo with bioluminescent imaging. Reproduction 2010; 140: 105-112. Impact factor: 3.262
(23.3%)
8. Chen CH, Tan SJ, Tzeng CR. In vivo fate mapping of cryopreserved murine ovarian grafts. J Ovarian Res. 2014 Aug;7:81.
Impact factor: 2.030 (56.7%)
9. Chen CH, Tzeng CR. Ovarian tissue transplantation: current state and research advancement. Curr Obstet Gynecol Rep.
2013 Dec;2(4):202-210. (Review article)
Correspondence
10. Tan SJ, Yeh YC, Shang WJ, Wu GJ, Liu JY, Chen CH. Protective effect of a gonadotropin-releasing hormone analogue on
chemotherapeutic agentinduced ovarian gonadotoxicity: A mouse model. Eur J Obstet Gynecol Reprod Biol 2010; 149:
182–185 Impact factor: 1.627 (57.7%)
11. Lin CK, Chang WH, Pan HH, Chen CH. Postpartum hellp syndrome with unusually high levels of liver enzymes. Taiwan J
Obstet Gynecol 2009 Sep; 48(3) Impact factor: 1.261 (73.1%)
12. Chen DC, Chen CH, Liu JY, Ku CH, Wu GJ. Serum vascular endothelial growth factor165 levels and uterine fibroid
volume. Acta Obstet Gynecol Scan 2005; 84(4):317-21. Impact factor: 1.985 (39.7%)
13. Su HY, Chen CH, Gao HW, Liu JY. A bicornuate uterus with a unilateral cornual adenomyosis. Obstet gynecol 2005 May;
105(5):1191-3. Impact factor: 4.368 (3.8%)
14. Wang YC, Su HY, Liu JY, Chang FW, Chen CH. Maternal and female fetal virilization caused by pregnancy luteomas.
Fertil Steril 2005 Aug;84(2):509 (SCI) Impact factor: 4.295 (5.1%)
15. Su HY, Liu HY, Chen CH. Pelvic inflammatory disease combined with perforated peptic ulcer -mimicking tubo-ovarian
abscess. Int J Gynaecol Obstet. 2005 Mar; 88(3):329-30. Impact factor: 1.563 (64.1%)
16. Su HY, Chen WH, Chen CH. Extra-pelvic endometriosis presenting as a vulvar mass in a teenage girl. Int J Gynaecol
Obstet. 2004 Dec; 87(3):252-3. Impact factor: 1.563 (64.1%)
17. Chang FW, Yu MH, Wu CC, Chen WH, Chen CH. Cornual pregnancy treated with dilatation and curettage under
laparoscopic guidance- a report of two cases. Taiwanese J Obstet Gynecol. 2004; 43(4):229-231. Impact factor: 1.261
(73.1%)
18. Wu CJ, Peng YJ, Yu MH, Chen CH*. Secretory adenocarcinoma of endometrium in a postmenopausal patient with breast
cancer using tamoxifen. Taiwanese J Obstet Gynecol 2007 Mar; 46( 1). Impact factor: 1.261 (73.1%)
19. Chang WH and Chen CH. Unilateral obstructive uropathy caused by deep infiltrating endometriosis. J Med Sci 2008;
28(2):99-102.
20. Chang WH, Lin CK, Chiang YJ, Chen CH. Puerperal hematoma combined with retroperitoneal dissection & obstructive
uropathy. J Med Sci 2008; 28(2): 81-84.
21. Chang WH, Liu JY, Yeh YC, Wu GJ, Chiang YJ, Yu MH, Chen CH*. Tubal ligation via colpotomy or laparoscopy: a
retrospective comparative study. Arch Gynecol Obstet. 2011; 283:805-808 Impact factor: 1.279 (71.8%)
22. Lin YH, Chang FW, Chen CH . Perimenopausal amenorrhea with cervical atresia and hematotrachelos. Journal of Medical
Sciences 2010 Aug; 30(4).
23. Lin YS, Yeh YC, Tzeng CR, Shang WJ, Wu GJ, Liu JY and Chen CH. Evaluating the effects of immunosuppression by in
vivo bioluminescence imaging after allo-transplantation of ovarian grafts. Reproductive Biomedical Online 2010;
22:220-227. Impact factor: 2.980 (15.4%)
24. Tsai YC, Tzeng CR, Wang CW, Hsu MI, Tan SJ, Chen CH. Antiapoptotic agent sphingosine-1-phosphate protects vitrified
murine ovarian grafts. Reprod Sci. 2014 Feb;21(2):236-43. Impact factor 2.179 (33.3%)
25. Tan SJ, Lee LJ, Tzeng CR, Wang CW, Hsu MI, Chen CH. Targeted anti-apoptosis activity for ovarian protection against
chemotherapy-induced ovarian gonadotoxicity. Reproductive Biomedical Online. 2014 (IN PRESS) Impact factor: 2.980
(15.4%)
Co-author
26. Zhang X, Chen CH, Confino E, Barnes R, Milad M, Kazer RR. Increasing endometrial thickness is associated with
improved treatment outcome for selected patients undergoing in vitro fertilization-embryo transfer. Fertil Steril 2005;
83:336-40. Impact factor: 4.295 (5.1%)
27. Wang YC, Chen CH, Su HY, Li HS, Liu Y. Huge spindle cell hemangioma of the cervix-mimicking a pelvic tumor.
Gynecol Obstet Invest 2005 April 27; 60(2):98-101. Impact factor: 1.251 (74.4%)
28. 26. Wang YC, Liu JJ, Chen CH, Peng YJ, Yu MH. Peritoneal tuberculosis mimicking ovarian cancer can be diagnosed by
polymerase chain reaction: a case report. Gynecol Oncol 2005 Jun; 97(3):961-963 Impact factor: 3.687 (9.0%)
29. Chen DC, Chen CH, Su HY, Yu CP, Chen WH, Yu MH. Retroperitoneal lymphangiomyomas presenting as a pelvic mass.
Acta Obstet Gynecol Scand 2005 Sep; 84(9):917-20. Impact factor: 1.985 (39.7%)
30. Chang WH, Chen CH, Yu MS. Conservative therapy of stage I endometrial adenocarcinoma and atypical endometrial
hyperplasia for the preservation of fertility. Int J Gynaecol Obstet. 2006; 92(2):137-8 Impact factor: 1.563 (64.1%)
31. Wang YC, Chen CH, Su HY, Yu MH. The impact of maternal cardioversion on fetal haemodynamics European Journal of
Obstetrics & Gynecology and Reproductive Biology 2006 Jun 1; 126(2):268-274. Impact factor: 1.627 (57.7%)
32. Chen DC, Ku CH, Huang YC, Chen CH, Wu GJ. Urinary nitric oxide metabolite changes in spontaneous and induced onset
active labor. Acta Obstet Gynecol Scand. 2004 Jul; 83(7):641-6. Impact factor: 1.985 (39.7%)
33. Chen DC, Chen CH, Su HY, Yu CP, Chen WH, Chu TY. Huge pedunculated fibroma of the vulva. Acta Obstet Gynecol
Scand 2004; 83:1091-2. Impact factor: 1.985 (39.7%)
34. Chang FW, Chen CH, Liu JY. Early diagnosis of ovarian pregnancy by ultrasound. Int J Gynaecol Obstet. 2004 May;
85(2):186-187. Impact factor: 1.563 (64.1%)
35. Huang HC, Chen CH, Chu CC, Yu CP, Chu TY. Mature cystic teratoma of ovary with gliomatosis peritonei. J Med Sci
2004; 24(6):343-346.
36. Chang FW, Yu MH, Ku CH, Chen CH, Wu GJ, Liu JY. Effect of uterotonics on intra-operative blood loss during
laparoscopy-assisted vaginal hysterectomy: a randomised controlled trial. BJOG 2006 Jan; 113(1):47-52. Impact factor:
3.862 (7.7%)
37. Ding DC, Huang RL, Chen CH, Chao CF, Chu TY. Novel germline and somatic mutations of the MSH2 gene in hereditary
non-polyposis colorectal cancer. Clin Genet 2007; 71: 190–192. Impact factor: 3.652 (29.9%)
38. Wu GJ, Chang FW, Lee SS, Cheng YY, Chen CH, Chen IC. Apoptosis-related phenotype of ejaculated spermatozoa in
patients with varicocele. Fertility Sterility 2009 Mar; 91(3):831-837. Impact factor: 4.295 (5.1%)
39. Liu YL, Chen CH, Liu JY, Chang FW, Chen IC, Chien HH, Wu GJ. Influence of late follicular luteinizing hormone
concentrations on ovarian response and fertilization outcome in patients undergoing in vitro fertilization with a short
protocol. J Med Sci 2009; 29(4):195-198.
40. Chen HC, Sytwu JK, Chang JL, Wang HW, Chen HK, Kang BH, Liu DW, Chen CH, Chao TT, Wang CH. Hypoxia
enhances the stemness markers of cochlear stem/progenitor cells and expands sphere formation through activation of
hypoxia-inducible factor-1 alpha. Hearing Research 2010; 275:43-52. Impact factor: 2.848 (9.1%)
41. Chen HS, Ma HI, Sytwu HK, Wang HW, Chen CCV, Liu SC, Chen CH, Chen HK and Wang CH. Neural stem cells secrete
factors thatpromote auditory cell proliferation via a leukemia inhibitory factor signaling pathway. J Neurosci Res. 2010 Nov
15; 88(15):3308-3318. Impact Factor: 2.986 (45.2%). Impact factor 2.729 (56.2%)
42. Liang SJ, Hsu CS, Tzeng CR, Chen CH, Hsu MI. Clinical and biochemical presentation of polycystic ovary syndrome in
women between the ages of 20 and 40. Hum Reprod. 2011 Dec ;26(12):3443-3449. Impact factor 4.585(2.6%)
43. Lin HC, Chen CH, Su HY. Bier's Spots on Legs Associated with Deep Vein Thrombosis during Pregnancy. Taiwan J Obstet
Gynecol. 2013 Mar (in print). Impact factor: 1.261 (73.1%)
44. Wu HM, Tzeng CR, Chen CH, Chen PH. Pelvic endometriosis with peritoneal fluid reduces pregnancy rates in women
undergoing intrauterine insemination. Taiwan J Obstet Gynecol. 2013 Dec;52(4):512-515. Impact factor: 1.261 (73.1%)
45. Tzeng CR, Chang YC, Chang YC, Wang CW, Chen CH, Hsu MI. Cluster analysis of cardiovascular and metabolic risk
factors in women of reproductive age. Fertil Steril. 2014 May;101(5): 1404-1410. Impact factor: 4.295 (5.1%)
46. Wang MH, Chen CH, Wang CW, Hsu MI, Tzeng CR. A higher anti-Müllerian hormone level is associated with an
increased chance of pregnancy in patients undergoing controlled ovarian stimulation and intrauterine insemination. J Obstet
Gynaecol. 2014 Jul; Epub ahead of print. Impact factor: 0.604 (92.3%)
學術獎項
論文著作:
Yi-Hsin Lin, Yu-Chi Yeh, Chii-Ruey Tzeng, Wei-Jen Shang,Jah-Yao Liu, Chi-Huang Chen* (責任作
者).Evaluating the effects of immunosuppression by in-vivo bioluminescence imaging after
allotransplantation of ovarian grafts. Reproductive BioMedicine Online. 2011 Feb;22(2):220–227.
國際醫學期刊優秀論文獎RBM Online 2011 年度最佳論文獎第二名
學術會議:
1. Chen CH, Wang CW, Hsu MI, Chen PH, Tzeng CR. In vivo immature testicular tissue engineering
for male fertility preservation - a transgenic mouse model.
American Society for Reproductive Medicine (ASRM). Boston, USA 2013. (第一名)
2. Chen CH, Wang CW, Hsu MI, Tzeng CR. Tracking the development potential and the onset
inhibition of primordial follicle of the cryopreserved murine ovary with bioluminescent imaging (BLI)
in vivo.
The International Ovarian Conference (IOC). Tokyo, Japan 2012. (第三名)
3. Chen CH, Wang CW, Hsu MI, Tzeng CR. 抗凋零劑SlP 對卵巢在化療毒性的保護效應Protective
effect of sphingosine l-phosphate on chemotherapeutic agent -induced ovarian gonadotoxicity.
Taiwanese Society for Reproductive Medicine (TSRM). Tainan, Taiwan 2011. (優秀論文獎)
4. Chen CH, Wu GJ, Liu JY, Tzeng CR. Protective effect of a gonadotropin-releasing hormone analogue
on chemotherapeutic agent-induced ovarian gonadotoxicity: A mouse model.
Fertilink and International Ovarian Conference. Kyoto, Japan 2010. (優秀論文獎)
5. Chen CH, Shang WJ, Tan SJ, Wu GJ,Liu JY, Tzeng CR, Tsai YC. Reconstitution of spermatogenesis
from testis failure after spermatogonial stem cells (SSC) transplantation for male fertility preservation -
A transgenic mouse model.
The Pacific Rim Society for Fertility and Sterility (PRSFS). Taipei, Taiwan 2009. (優秀論文獎)

美國生殖醫學會2012年會發表研究作品於San Diego

TARGETED ANTIAPOPTOTIC AGENTS FOR OVARIAN PROTECTION ON CHEMOTHERAPEUTIC AGENT-INDUCED OVARIAN TOXICITY

 

Chi-Huang Chen1, Chia-Woei Wang1, Ming-I Hsu2, Chii-Ruey Tzeng1

                            
Center for Reproductive Medicine & Sciences, Taipei Medical University Hospital, Taiwan1, Department of Obstetrics & Gynecology, Wan Fang Hospital,Taipei Medical University, Taiwan2

 

Introduction                                    

Gonadotoxicity after alkylating agent is a well known complication. We aim to investigate the protective effect of S1P, an apoptosis-inhibitor, on chemotherapy-induced ovarian toxicity.

 

Design: Animal study    

 

Material & Methods

Twelve 8-week old female FVB/NJNarl mice were randomly divided into four groups: control (n=3), busulfan (B, n=3), low concentration of S1P plus busulfan (S1PL + B, n=3) and high concentration of S1P plus busulfan (S1PH + B). In the S1P + B group, 0.5 mM of S1P, prepared in a vehicle (PET), was injected into the bursa of one ovary (S1PL + B group, n=3), and 2.0 mM of S1P in PET was injected into the bursa of the contralateral ovary as the S1PH + B group (n=3). Only PET was injected into the bursa of both ovaries in the B (n=3) and control groups (n=3). One hour later, mice in the B and S1P + B groups were injected with busulfan intraperitoneally at a dose of 36 mg/kg. After 4 weeks, all mice were evaluated the whole ovaries of follicle number by H&E stain, expression of AMH and GDF-9 by RT-PCR. Immunohistochemistry of Caspase-3 assayed for the ovarian apoptosis 24 and 72 hours after busulfan treatment was compared the difference.

 

Results

Obvious destruction of ovarian structure, significant depletion of follicles and the decreased lowest levels of AMH and GDF-9 were demonstrated in the group B among the four groups (< 0.01). Mice pretreated with S1P (S1PL + B group or S1PH + B group) revealed lower follicle counts and levels of AMH and GDF-9 than that of the control group (p<0.01). Active fragments of caspase-3 showed much more in busulfan-treated group than that of other three groups.

 

 

Conclusions

S1P is an ovarian protective agent that prevents chemotherapy-induced gonadotoxicity. Immunohistochemistry of caspase-3 evidences the significant ovarian toxicity after busulfan treatment without S1P protection. The follicle counts and levels of AMH and GDF-9 are direct and reliable parameters for evaluating the ovarian reserve, and potentially utilized as markers to assess female fertility and detect the impact of chemotherapy. We suggest that S1P pretreatment is a promising option for fertility preservation.

 

 

 

Supported by: NSC99-2314-B-016-013-MY3, Taiwan, ROC

台灣生殖醫學會2011年會:Prize poster winner (陳啟煌)

今年陳啟煌醫師獲100年臺灣生殖醫學會年會

優秀海報論文獎

 

 

抗凋零劑S1P對卵巢在化療毒性的保護效應

 

 

 

       與北醫生殖中心工作同仁合影

國際優秀論文獎RBM Online2011年全年度第二名





 

試管嬰兒之父也是諾貝爾醫學獎得主Robert G Edwards創立的不孕症第三名期刊Reproductive BioMedicine Online宣布我指導的論文榮獲2011年年度最佳4篇論文之第二名,我研究的主題是生物冷光活體追蹤同種老鼠間卵巢移植以免疫排斥藥治療的效應。我的排名放最後表示為此篇通訊作者 (責任作者),就是指導作者之意,台灣第一次有人(在下我)獲此殊榮。

 

PS: 被指導的林宜欣醫師因此篇獲得美國第一名的

 

約翰霍普金斯大學博士入學申請!

 

21 June 2012

 

 

Dear Dr Chen

 

Robert G. Edwards Prize Paper Award for 2011

 

Congratulations! Today, we, as editors of Reproductive BioMedicine Online, are pleased to announce on the journal website [http://www.rbmojournal.com/home] that a paper from your laboratory appears in connection with the 2011 annual Robert G. Edwards Prize Paper Award for the best paper published in the journal in that year. This award has been established by Elsevier Ltd. for the purpose of recognizing excellence in our field of study, and will be awarded annually. All original research or review articles published in journal volumes 22 and 23 (including Ethics, Bioscience and Life, but excluding supplements) have been considered for this prize.

 

The winning author(s) receive a certificate of recognition, 1000 Euros, and a complimentary ScienceDirect Ambassador Account.  SD Ambassadors receive full access to the entire library of books and journals published by Elsevier. In addition, the prize-winning paper will be made open access. Where the prize goes to a multi-author paper, the more junior of the main authors receives the one year’s access to the entire Elsevier Science Direct database. All names will appear on the award certificate.

 

 

 

 

 

Congratulations on making it to this highly competitive short list stage. The winner will be announced on 28th June.

 

Yours truly

 

Jacques Cohen

Gedis Grudzinskas

Martin Johnson

 

 

The four short listed papers for the 2011 prize are:


Ooplast-mediated developmental rescue of bovine oocytes exposed to ethidium bromide by Marcos Roberto Chiaratti, Christina Ramires Ferreira, Felipe Perecin, Simone Cristina Meo, Juliano Rodrigues Sangalli, Lıgia Garcia Mesquita, Julio Cesar de Carvalho Balieiro, Lawrence Charles Smith, Joaquim Mansano Garcia, Flavio Vieira Meirelles in Reproductive BioMedicine Online 22, 172–183.


 

Differential transcriptomic profile in spermatozoa achieving pregnancy or not via ICSI by Sandra Garcıa-Herrero, Nicolas Garrido, Jose´ Antonio Martınez-Conejero,
Jose´ Remohı´, Antonio Pellicer, Marcos Meseguer in Reproductive BioMedicine Online 22, 25– 36.


Meiosis errors in over 20,000 oocytes studied in the practice of preimplantation aneuploidy testing by Anver Kuliev , Zev Zlatopolsky, Irina Kirillova, Julia Spivakova,
Jeanine Cieslak Janzen in Reproductive BioMedicine Online 22, 2– 8.

 


Evaluating the effects of immunosuppression by in-vivo bioluminescence imaging after allotransplantation of ovarian grafts by Yi-Hsin Lin, Yu-Chi Yeh, Chii-Ruey Tzeng, Wei-Jen Shang, Jah-Yao Liu, Chi-Huang Chen in Reproductive BioMedicine Online 22, 220– 227.